Antitargets and Drug Safety (Methods & Principles in Medicinal Chemistry Book 66) 1st Edition

Antitargets and Drug Safety (Methods & Principles in Medicinal Chemistry, Book 66) – 1st Edition is an authoritative and highly specialized reference that addresses one of the most critical challenges in modern drug development: drug safety and off-target effects. This book is essential reading for medicinal chemists, pharmaceutical scientists, toxicologists, pharmacologists, and advanced postgraduate students involved in drug discovery and development.

The book focuses on antitargets—biological targets whose unintended interaction with drug candidates can lead to toxicity, adverse drug reactions, or late-stage clinical failure. By understanding these antitargets early in the drug development process, researchers can significantly reduce attrition rates and improve the safety profile of new therapeutic agents.

Key Features

• In-depth coverage of antitargets in drug discovery

• Focus on drug safety and adverse effect mechanisms

• Detailed discussion of cardio-, hepato-, and neurotoxicity

• Modern tools for early safety and toxicity prediction

• Integration of medicinal chemistry and toxicology principles

• Expert-authored chapters with scientific depth

• Part of the renowned Methods & Principles in Medicinal Chemistry series

• Ideal for researchers, professionals, and postgraduate students

• Comprehensive 1st Edition reference for safer drug design