Translational Cardiology (Handbook for Designing and Conducting Clinical and Translational Research) 1st Edition

Hypertrophic Cardiomyopathy Third Edition 2025 the booklanceby Srihari S. Naidu (Editor)This extensively updated textbook provides a comprehensive review of hypertrophic cardiomyopathy (HCM), the most common genetic disorder of the heart characterized by dysfunctional contractility at the sarcomere level. The disease produces abnormal and often focal hypertrophy on a macroscopic level that further impairs cardiac performance and may lead to life-threatening arrhythmias. There have been vast changes in the understanding and management of the disease in recent years, in addition to increased awareness and prevalence. Accordingly, HCM Centers of Excellence have rapidly grown across the world that are in need of detailed information on the topic. This edition provides a practical yet comprehensive approach to both diagnosis and management, establishing evidence-based best practice for all scenarios. Hypertrophic Cardiomyopathy provides readers with key points and critical clinical pearls to assist them in managing patients. Every chapter has been updated to reflect the huge changes across the topic over the past 5 years. Each chapter is supplemented by a series of relevant instructional multiple choice questions and their solutions are included in the supplemental FlashCards. All aspects of treatment are covered – traditional and novel medications, pacemakers and defibrillators, and invasive septal reduction therapy (both surgical myectomy and alcohol septal ablation) – in addition to genetics, family screening, lifestyle concerns and athletic screening. Nuanced areas such as HCM in pregnancy or in the critical care unit, or the approach to HCM and hypertension, are also addressed. The practical approach has been reinforced with an expanded emphasis on creating a Center of Excellence, how to facilitate the multi-disciplinary approach, and on real-world case-based reviews and discussions. Written by experts across the globe, this is an essential textbook for cardiology professionals from trainee to board-certified physician, including important information for interventional cardiologists, cardiac surgeons, cardiac imagers, critical care physicians, sports medicine physicians, genetic counsellors and electrophysiologists.